Cart
sales@molnova.com
Home - Products - Membrane Transporter/Ion Channel - Proton Pump - Azeloprazole sodium

Azeloprazole sodium

CAS No. 955095-47-3

Azeloprazole sodium( E-3710 | Z-215 )

Catalog No. M16818 CAS No. 955095-47-3

A novel potent, orally active proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Azeloprazole sodium
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel potent, orally active proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM.
  • Description
    A novel potent, orally active proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM; inhibits histamine-stimulated gastric acid secretion with ED50 of 0.18-0.2 mg/kg in gastric fistula model in dogs, displays 2.3-fold more potency over Esomeprazole.Other Indication Phase 1 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    E-3710 | Z-215
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Proton Pump
  • Recptor
    Proton Pump
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    955095-47-3
  • Formula Weight
    452.525
  • Molecular Formula
    C22H27N3NaO4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1=CN=C(C(=C1OCC2COC(OC2)(C)C)C)CS(=O)C3=NC4=CC=CC=C4[N-]3.[Na+]
  • Chemical Name
    (R)-2-(((4-((2,2-Dimethyl-1,3-dioxan-5-yl)methoxy)-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzimidazole, sodium salt

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kodama K, et al. J Pharmacol Exp Ther. 2010 Aug;334(2):395-401. 2. Toda R, et al. J Clin Pharmacol. 2017 Nov 28. doi: 10.1002/jcph.1038. 3. Toda R, et al. Xenobiotica. 2017 Nov 2:1-15. doi: 10.1080/00498254.2017.1390625.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • TAK-438 free base

    A novel potent, oral potassium-competitive acid blocker (P-CAB) that potently inhibits H+,K+-ATPase with IC50 of 19 nM.

  • Bamaquimast

    Bamaquimast is an inhibitor of proton pump.

  • Ilaprazole

    A potent, orally active proton pump inhibitor that irreversibly inhibits H+/K(+)-ATPase with IC50 of 6 uM.

Sign In Join Free